PF3D7_1434300 Hsp70/Hsp90 organizing protein

Immunofluorescence staining to detect Hsp40, HSP70, HSP90 and HOP was conducted on trophozoite stage P. falciparum-infected erythrocytes. Panels show from left to right a DIC image, distribution of protein of interest (POI), nuclear stain (Hoechst), merge and overlay (localization relative to the parasite nucleus and phase-contrast image). All proteins showed cytosolic localization.

Botha M, Chiang AN, Needham PG, Stephens LL, Hoppe HC, K├╝lzer S, Przyborski JM, Lingelbach K, Wipf P, Brodsky JL, Shonhai A, Blatch GL. Plasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shock. Cell Stress Chaperones. 2011 16(4):389-401. Pictures were kindly provided by Jude Przyborski.

Other associated proteins

PFID Formal Annotation
PF3D7_0708400 heat shock protein 90
PF3D7_0818900 PfHsp70-1
PF3D7_1437900 HSP40, subfamily A