Localization of PfH45 by immunofluorescence staining. The cells were fixed and immunostained with purified primary antibodies against PfH45 followed by FITC-labeled secondary antibody (green) and then counterstained with DAPI (blue). Stage: (a) ring; (b) trophozoite and (c) schizont. PfH45 is localized throughout the parasite, suggesting mainly cytoplasmic localization.

Pradhan A, Tuteja R. Bipolar, Dual Plasmodium falciparum helicase 45 expressed in the intraerythrocytic developmental cycle is required for parasite growth. J Mol Biol. 2007 373:268-81. Copyright Elsevier 2010.