RESA labeling of P. falciparum merozoite dense granules (protein A-5-nm gold; bars, 0.2 ,mm). FIG. 2 and 3. Sections of D10 merozoites with labeled dense granules after incubation with MAb23/9. FIG. 4 and 5. Sections of D10 merozoites with rhoptries (R) in view after incubation with human anti-RESA, preparation H145. FIG. 6. Disrupted D10 merozoites with labeled dense granules (MAb23/9). ports. The studies described here show that P. falciparum RESA is localized to dense round granules (of up to 100 nm in diameter) in merozoites and to similar-sized aggregates of amorphous material in the parasitophorous vacuole of newly invaded erythrocytes.
Culvenor JG, Day KP, Anders RF. Plasmodium falciparum ring-infected erythrocyte surface antigen is released from merozoite dense granules after erythrocyte invasion. Infect Immun. 1991 59:1183-1187.