PfEMP1 PfEMP1

KAHsp40 associates with knobs on the infected erythrocyte membrane. (A-B) IFA reveals that KAHsp40 and KAHRP co-localize in the erythrocyte periphery near the erythrocyte plasma membrane. White arrows indicate the discrete foci in which they co-localize. KAHsp40 and PfEMP1 and KAHsp40 and PfEMP3 co-localize with each other on the erythrocyte plasma membrane indicating the close association of KAHsp40 with knobs.

Acharya P, Chaubey S, Grover M, Tatu U. An Exported Heat Shock Protein 40 Associates with Pathogenesis-Related Knobs in Plasmodium falciparum Infected Erythrocytes. PLoS One. 2012;7(9):e44605.

Other associated proteins

PFID Formal Annotation
PF3D7_0201800 knob associated heat shock protein 40
PF3D7_0201900 erythrocyte membrane protein 3
PF3D7_1370300 membrane associated histidine-rich protein
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