Immunolocalization of PfEMP1 (a), PfEMP3 (b) and KAHRP (c) in rings (upper row) and mature torphozoites (lower row) using specific antibodies and visualization by confocal microscopy. PfEMP3 is deposited under the membrane of the infected RBC. Mutation of PfEMP3 disrupts transfer of PfEMP1 to the outside of infected cells.
Adapted by permission from Macmillan Publishers Ltd: Waterkeyn JG, Wickham ME, Davern KM, Cooke BM, Coppel RL, Reeder JC, Culvenor JG, Waller RF, Cowman AF. Targeted mutagenesis of Plasmodium falciparum erythrocyte membrane protein 3 (PfEMP3) disrupts cytoadherence of malaria-infected red blood cells. EMBO J. 2000 19:2813-23.
Other associated proteins
|PF3D7_0201900||erythrocyte membrane protein 3|