Localization and distribution of KAHRP in erythrocytes infected with P. falciparum. Erythrocytes were resealed without (A), with 40 mM GST (B), or with 40 mM GST-aR4 Spectrin (C). The resealed erythrocytes were infected with P. falciparum and cultured for 48 h. The localization of KAHRP was detected by immunostaining with anti-KAHRP antibody. Green, KAHRP; red: malaria DNA stained by TOPO-3.
Pei X, An X, Guo X, Tarnawski M, Coppel R, Mohandas N. Structural and functional studies of interaction between Plasmodium falciparum knob-associated histidine-rich protein (KAHRP) and erythrocyte spectrin. J Biol Chem. 2005 280:31166-71.