PF3D7_0930300 merozoite surface protein 1

Co-localization of PfMAg-1 with PfMSP-4 or PfMSP-119 at late schizont/merozoite parasites examined by confocal fluorescent microscopy. PfMSP-119 is the 19-kDa C-terminal fragment of PfMSP-1 that remains membrane-bound on the invading merozoite Top: Merozoite detected with antibodies X62c (against PfMAg-1) and α-PfMSP-4. Middle: Mature schizont detected with antibodies X62c and α-PfMSP-119. Bottom: Merozoite detected with antibodies X62c and α-PfMSP-119. Bright field images are shown on the left panel. PfMSP-1 and PfMSP-4 are two of the major merozoite surface proteins characterized. Schizonts/merozoite of 3D7 strain, PfMAg-1 co-localized very well with PfMSP-119, and partially with PfMSP-4, in the typical bunch-of-grapes fluorescence pattern haracteristic of merozoite surface proteins.

Gao YH, Li HL, Lu Y, Gao FM, Lin YH, Zhou HC, Zhang LH, Wang H. Identification of a vaccine candidate antigen, PfMAg-1, from Plasmodium falciparum with monoclonal antibody M26-32. Parasitol Res. 2009 105:1723-32. PMID: 19777263

Other associated proteins

PFID Formal Annotation
PF3D7_0207000 merozoite surface protein 4
PF3D7_0405200 cytosolically exposed rhoptry leaflet interacting protein 2