Expression of functional CDPK1 fusion proteins in 3D7 P. falciparum parasites Immunolocalisation of CDPK1 in late schizont stage parasites showing co-localisation with MSP1-19 and GAP45, proteins which reside on the plasma membrane and inner membrane complex, respectively. CDPK1 was detected with CDPK1-specific mouse monoclonal 3E6 and the other proteins with polyclonal rabbit antibodies .
Azevedo MF, Sanders PR, Krejany E, Nie CQ, Fu P, Bach LA, Wunderlich G, Crabb BS, Gilson PR. Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development. Biochem J. 2013 452(3):433-41
PubMed Article: Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0217500 | Calcium-dependent protein kinases; CDPK1 |
PF3D7_1222700 | glideosome-associated protein 45 |