ARO is late transcribed in blood stages of Plasmodium falciparum and co-localizes with the rhoptries. Co-localization of PfARO with (upper panel) the rhoptry marker RALP-1 (red) and (lower panel) the microneme marker EBA-181 (red). Nuclei stained with DAPI (blue). Enlargement of selected areas are marked with white square and referred as Zoom. Scale bar, 1 μm. Colocalization with the rhoptry bulb marker RALP-1 and the microneme marker EBA-181 identify PfARO as a rhoptry protein.

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