PF3D7_1133400 apical membrane antigen 1

Localization of CyRPA to the merozoite apex by immunofluorescence staining. P. falciparum 3D7 merozoites (A) or schizont stages (B) were coimmunostained with anti-CyRPA mAb c06 (red) and anti-GAPDH Abs (marker for cytosol), AMA-1 (marker for micronemes), RAP-1 (marker for rhoptry bulbs), MSP-1 (marker for merozoite surface), or MSP-5 (green). Nuclei were stained with DAPI (blue). Original magnification x1008. CyRPA is localized at the merozoite apex.

Dreyer AM, Matile H, Papastogiannidis P, Kamber J, Favuzza P, Voss TS, Wittlin S, Pluschke G. Passive immunoprotection of Plasmodium falciparum-infected mice designates the CyRPA as candidate malaria vaccine antigen. J Immunol. 2012 188(12):6225-37.

Other associated proteins

PFID Formal Annotation
PF3D7_0206900 merozoite surface protein 5
PF3D7_0423800 RH5-Ripr membrane anchoring protein cysteine-rich protective antigen
PF3D7_0501600 rhoptry-associated protein 2
PF3D7_0930300 merozoite surface protein 1
PF3D7_1462800 glyceraldehyde-3-phosphate dehydrogenase