Subnuclear Localization of PfRh4 Varies with Invasion Phenotype Switching. (A) Representative images of DNA FISH measuring the colocalization of active and silent PfRh loci (green) with Rep20 (red). (D) Schematic and representative images of DNA FISH localizing PfRh4 (green) and a plasmid containing transcriptionally active hDHFR (red) and localized to the nuclear periphery with Rep20 (gray).
Coleman BI, Ribacke U, Manary M, Bei AK, Winzeler EA, Wirth DF, Duraisingh MT. Nuclear Repositioning Precedes Promoter Accessibility and Is Linked to the Switching Frequency of a Plasmodium falciparum Invasion Gene. Cell Host Microbe. 2012 12(6):739-50. PMID:
PubMed Article: Nuclear repositioning precedes promoter accessibility and is linked to the switching frequency of a Plasmodium falciparum invasion gene
Other associated proteins