PF3D7_0501600 rhoptry-associated protein 2

Wide field IFA time course of invasion using A) anti-RAP1/PfRON4. Pre-egress shows standard wide-field image. Invasion images show IFA with deconvolution (single slice). Before invasion commencement, RAP1 clearly remained within the merozoite apex (RAP1 early) posterior to the rhoptry neck as defined by PfRON4. Midinvasion merozoites revealed that RAP1 labeling had moved to an anterior position beginning immediately adjacent to the junction and tracking the exterior of the merozoite as it entered (RAP1 mid). These observations show clearly RAP1 transition pre-, mid-, and postinvasion.

Riglar DT, Richard D, Wilson DW, Boyle MJ, Dekiwadia C, Turnbull L, Angrisano F, Marapana DS, Rogers KL, Whitchurch CB, Beeson JG, Cowman AF, Ralph SA, Baum J. Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte. Cell Host Microbe. 2011 9:9-20.

Other associated proteins

PFID Formal Annotation
PF3D7_1116000 rhoptry neck protein 4
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