PF3D7_0202000 knob-associated histidine-rich protein

Localization of PfEMP1, KAHRP, PfEMP3 and SBP1 in P. falciparum-infected erythrocytes. The first column of each panel shows a bright-field image, the second panel specific antibody and the third panel overlay of the previous two and a nuclear stain (DAPI). PfEMP1 displays and functions on the surface of infected erythrocytes. KAHRP and PfEMP3 are exported to the erythrocyte cytoplasm and interacts with Maurer’s clefts and eventually reach the inner side of the host cell membrane. SBP1 is a Maurer’s clefts resident protein.

Maier AG, Rug M, O'Neill MT, Brown M, Chakravorty S, Szestak T, Chesson J, Wu Y, Hughes K, Coppel RL, Newbold C, Beeson JG, Craig A, Crabb BS, Cowman AF. Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes. Cell. 2008 134:48-61.

Other associated proteins

PFID Formal Annotation
PF3D7_0201900 erythrocyte membrane protein 3
PF3D7_0501300 skeleton-binding protein 1