PF3D7_0903700 alpha tubulin 1

Schizont and merozoite culture was incubated overnight with 0.1┬ÁM cytochalasin D to inhibit invasion. Thin smeared on a glass slide, fixed in methanol, stained with commercial antibody against a-tubulin (mouse anti-tubulin DM1A, Sigma, 1:200). Two stripes are show from apex which are presumed to be the 2-3 microtubules present in the merozoite (see Fowler et al. Microtubule associated motor proteins of Plasmodium falciparum merozoites. Molecular and Biochemical Parasitology (2001) vol. 117 (2) pp.

Baum J, Tonkin CJ, Paul AS, Rug M, Smith BJ, Gould SB, Richard D, Pollard TD, Cowman AF. A malaria parasite formin regulates actin polymerization and localizes to the parasite-erythrocyte moving junction during invasion. Cell Host Microbe. 2008 3:188-98. Copyright Elsevier 2009.