Localization of PfHU. (A) Immunolocalization of PfHU using confocal microscopy. Panels show nuclear DNA staining with DAPI (1), PfHU fluorescence (2), MitoTracker Red signal (3) and their overlap (4) in a late trophozoite. The corresponding phase–contrast scan is shown in (5). (B) Co-localization of PfHU and apicoplast-targeted GFP. Nuclear DNA stained with DAPI (1), PfHU signal (2), GFP signal (3) and their overlay (4) are shown. PfHU is associated with apicoplast DNA and is involved in DNA compaction.

Ram EV, Naik R, Ganguli M, Habib S. DNA organization by the apicoplast-targeted bacterial histone-like protein of Plasmodium falciparum. Nucleic Acids Res. 2008 36(15):5061-73.