Cytochemical localization of the P. falciparum M18AAP. A, indirect immunofluorescence of D10 wild-type parasites probed with polyclonal antisera to native PfM18AAP. B, indirect immunofluorescence of PFI1570c-GFP transgenic parasites probed with specific antisera to GFP. C, direct fluorescence on live PFI1570c-GFP transgenic parasites. Parasite nuclei were visualized with Hoechst dye (blue). Specific staining was observed in the cytosol of the ring and schizont stage parasites (green, fluorescein isothiocyanate).

Teuscher F, Lowther J, Skinner-Adams TS, Spielmann T, Dixon MW, Stack CM, Donnelly S, Mucha A, Kafarski P, Vassiliou S, Gardiner DL, Dalton JP, Trenholme KR. The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum. J Biol Chem. 2007 282:30817-30826.