Upper panel: Immuno-localization of the FIKK12-GFP chimera in transgenic parasites. First image GFP fluorescence, second image cells incubated with anti-FIKK12 antibody, third image overlay of first and second image showing that FIKK12-GFP colocalizes with anti-FIKK12 at the surface of the infected RBC.

Lower panel: Colocalization of FIKK12 with PfSBP1 in ring stage P. falciparum-infected erythrocytes. Second row: colocalization is lost at the trophozoite stage.

Nunes MC, Goldring JP, Doerig C, Scherf A. A novel protein kinase family in Plasmodium falciparum is differentially transcribed and secreted to various cellular compartments of the host cell. Mol Microbiol. 2007 63:391-403.