PF3D7_1246100 delta-aminolevulinic acid synthetase

Localization of porphobilinogen deaminase PfPBGD with d-aminolevulinate dehydratase PfALAD and d-aminolevulinic acid synthase PfALAS in P. falciparum by immunofluorescence. PGDB and PfALAD are localized to the apicoplast. PfALAS is localized to the mitochondrion. IE, infected erythrocyte; P, parasite; H, hemozoin.

Sato S, Clough B, Coates L, Wilson RJ. Enzymes for heme biosynthesis are found in both the mitochondrion and plastid of the malaria parasite Plasmodium falciparum. Protist. 2004 155:117-25. Copyright Elsevier 2009.

Other associated proteins

PFID Formal Annotation
PF3D7_1209600 porphobilinogen deaminase
PF3D7_1440300 delta-aminolevulinic acid dehydratase porphobilinogen synthase, HemB