Colocalization of histone H3 marks with PfSET10. Shown are from top to bottom: H3K4m1, H3K4m2, H3K4m3, and H3K9ac. The histone marks (red) were detected using specific antibodies and colocalized with PfSET10-HA (green) using anti-HA antibodies. Nucleus position is shown by DAPI staining. PfSET10 colocalized with the H3K4me1, me2, and me3 marks in the perinuclear region, which is also marked by H3K9ac
Volz JC, Bártfai R, Petter M, Langer C, Josling GA, Tsuboi T, Schwach F, Baum J, Rayner JC, Stunnenberg HG, Duffy MF, Cowman AF. PfSET10, a Plasmodium falciparum methyltransferase, maintains the active var gene in a poised state during parasite division. Cell Host Microbe. 2012 11(1):7-18.
Other associated proteins
|PF3D7_1221000||histone-lysine N-methyltransferase, H3 lysine-4 specific|