PF3D7_1221000 histone-lysine N-methyltransferase, H3 lysine-4 specific

Identification of proteins that localize to the active var gene expression site. The table below shows proteins uniquely identified in the 3D7SET10-HA pull-down along with the number of unique peptides obtained. The PfIDs of the genes identified are shown along with their functional annotation.

IFA of PfSET10 (green) and PfActin-1 (red) with the nucleus (blue) stained with DAPI. La R=late ring, Ea T=early trophozoite.

Volz JC, Bártfai R, Petter M, Langer C, Josling GA, Tsuboi T, Schwach F, Baum J, Rayner JC, Stunnenberg HG, Duffy MF, Cowman AF. PfSET10, a Plasmodium falciparum Methyltransferase, Maintains the Active var Gene in a Poised State during Parasite Division. Cell Host Microbe. 2012 11(1):7-18.

Other associated proteins

PFID Formal Annotation
PF3D7_1224300 polyadenylate-binding protein 1, putative