Characterization of PfGAP50 and PfGAP45 proteins. rabbit antiserum against recombinant PfGAP50 localizes to the merozoite periphery and remains following rupturing of schizont, consistent with localization to the IMC. The white arrows on putative invading merozoite point to interface with erythrocyte where increased fluorescence is detectable, possibly indicating concentration at the moving junction. Rabbit antiserum against recombinant PfGAP45 similarly suggests localization to the IMC. A second putative invading merozoite also suggests PfGAP45 is concentrated at the interface (white arrows) with the erythrocyte, consistent with the moving junction. Scale bar, 1 mm.
Baum J, Richard D, Healer J, Rug M, Krnajski Z, Gilberger TW, Green JL, Holder AA, Cowman AF. A conserved molecular motor drives cell invasion and gliding motility across malaria life cycle stages and other apicomplexan parasites. J Biol Chem. 2006 281(8):5197-208.
Other associated proteins
|PF3D7_1222700||glideosome-associated protein 45|