Cellular localization of A-type Rifin, Stevor and Surfin 4.2 in FIKK-KO and wild type parasites. Antigen was detected using specific anti-Rifin, Surfin or Stevor antibodies by immunofluorescence assay. The genes of these three families are ocated close or within the subtelomeric chromosomic region. And different protein members have been localized in the infected erythrocytes’ Maurer’s clefts. Similar immunofluorescence patterns were detected in infected erythrocytes with mature stages of FIKK7.1-KO, FIKK12-KO and FCR3 parental parasites.
Nunes MC, Okada M, Scheidig-Benatar C, Cooke BM, Scherf A. Plasmodium falciparum FIKK kinase members target distinct components of the erythrocyte membrane. PLoS One. 2010 5(7):e11747.
Other associated proteins
|PF3D7_0726200||serine/threonine protein kinase, FIKK family|