PF3D7_1017300 golgi re-assembly stacking protein 2

Live images of transgenic parasites expressing PfGRASP-GFP were visualized by confocal microscopy. In ring-stage parasites (8-16 hours post invasion, a-b) PfGRASP-GFP is restricted to one compartment in close proximity to the nucleus (blue). A second Golgi is generated prior to nuclear division (24 hours post invasion, c). As the parasite matures, nuclear division commences and is accompanied by multiplication of the Golgi (32-40 hours post invasion, d-e). The parasite has nearly reached the final stage of schizogony where each forming merozoite will be equipped with one Golgi and nucleus (46 hours post invasion, f). Each merozoite has inherited one Golgi (0 hours, g).

Reproduced with permission from Struck et al., 2005: Re-defining the Golgi complex in P. falciparum using the novel Golgi marker PfGRASP. J. Cell Sci. 118: 5603-13.

img