Immunofluorescence detection of MSP-636 in acetone-fixed P. falciparum T9:96 schizonts. Panels A to C show the reaction with antibodies raised to a recombinant fusion protein containing the last 45 amino acids of MSP-6; panels D, E, and F show the reaction of MSP-1 specific mAbs X509, 1E1 and 8A12, respectively. MSP-636 is the processed product of the precursor merozoite surface protein 6 (MSP-6). Results show that antibodies bound to antigen at the parasite surface or in the parasitophorous vacuole within schizonts, with a pattern indistinguishable from that of antibodies to MSP-1.

Trucco C, Fernandez-Reyes D, Howell S, Stafford WH, Scott-Finnigan TJ, Grainger M, Ogun SA, Taylor WR, Holder AA. The merozoite surface protein 6 gene codes for a 36 kDa protein associated with the Plasmodium falciparum merozoite surface protein-1 complex. Mol Biochem Parasitol. 2001 112:91-101. . Copyright Elsevier 2010.