A. Thioflavin-T staining of egressed schizonts along with DAPI suggests presence of amyloid coat on the merozoite surface. (B) Confocal assay visualizing hemozoin crystals stained by anti-MSP3 Abs.(C) Immuno electron microscopy using anti–MSP3 Abs showed peripheral localization of MSP3 over merozoite surface. Merozoites immunostained with anti-MSP3 Abs revealed novel long fibrillar assemblies associated with the surface, possessing characteristics often attributed to amyloid like structures including fibril morphology and binding to ThT.

Imam M, Singh S, Kaushik NK, Chauhan VS. Plasmodium falciparum Merozoite Surface Protein 3: oligomerization, self-assembly and heme complex formation. J Biol Chem. 2013 289(7):3856-68 PMID: