PF3D7_0400400 erythrocyte membrane protein 1, PfEMP1

Immunofluorescence assay with antisera to HB3var3 (1/100 dilution) showing punctate surface fluorescence on live infected erythrocytes typical of PfEMP1 antibodies. This groupA-like var genes was highly transcribed in three P. falciparum strains selected for adhesion to anHBEC line.

Claessens A, Adams Y, Ghumra A, Lindergard G, Buchan CC, Andisi C, Bull PC, Mok S, Gupta AP, Wang CW, Turner L, Arman M, Raza A, Bozdech Z, Rowe JA. A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells. Proc Natl Acad Sci U S A. 2012 109(26):E1772-81.

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