Upper panel: NIC interacts specifically with MSP-119 of Plasmodium falciparum. Fluorescent microscopy analyses using NIC-biotin reveals the target on merozoite surface, co-localizing with MSP-119-GFP
Lower panel: Co-localization of MSP-1 (using an antibody) and NIC-biotin using immunofluorescence microscopy ,
Chandramohanadas R, Basappa, Russell B, Liew K, Yau YH, Chong A, Liu M, Gunalan K, Raman R, Renia L, Nosten F, Shochat SG, Dao M, Sasisekharan R, Suresh S, Preiser P. Small Molecule Targeting Malaria Merozoite Surface Protein-1 (MSP-1) Prevents Host Invasion of Divergent Plasmodial Species. J Infect Dis. 2014 May 26. [Epub ahead of print]