Localization and expression of endogenous SEMP1 in 3D7 wild-type parasites. IFAs of MeOH-fixed RBCs infected with 3D7 wild-type parasites synchronized at timepoints 6–14 hours post invasion (hpi), 16–24 hpi, 26–34 hpi and
36–44 hpi. Cells were co-labelled with mouse a-SEMP1 and rabbit a-MAHRP1 serum. Dual-labelling IFAs of sorbitol-synchronized parasites at 6–14 hours post invasion (hpi), 16–24 hpi, 26–34 hpi, and 36–44 hpi showed that SEMP1, similarly to MAHRP1, is exported early after invasion to MCs where it partially co-localized with MAHRP1
Dietz O, Rusch S, Brand F, Mundwiler-Pachlatko E, Gaida A, Voss T, Beck HP. Characterization of the Small Exported Plasmodium falciparum Membrane Protein SEMP1. PLoS One. 2014 9(7):e103272.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_1370300 | membrane associated histidine-rich protein |