Comparison of PfSec12 localization with markers for the ER and Golgi. Parasites were cotransfected with plasmids for expression of mRFP-PfSec12 (from the native pfsec12 5′ UTR) with either (A) GFP-SDEL, a marker for the general ER, or (B) PfGRASP-GFP, a cis-Golgi marker. mRFP-PfSec12 was localized throughout the ER coincident with GFP-SDEL, in close apposition to PfGRASP-labelled Golgi. Bar = 5 μm.
Lee MC, Moura PA, Miller EA, Fidock DA. Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif. Mol Microbiol. 2008 68(6):1535-46.
Other associated proteins
|PF3D7_1017300||golgi re-assembly stacking protein 2|
|PF3D7_1116400||guanine nucleotide-exchange factor SEC12|