Left Panel: Live cell imaging of parasites expressing PfSec24-GFP (PF13_0324), with nuclei stained with Hoechst 33342. PfSec24a marks distinct foci that likely represent transitional ER sites that are enriched in the COPII vesicle machinery. Parasites at the ring (row 1), trophozoite (row 2), early schizont (row 3) and late schizont (row 4) stages, as well as released merozoites (row 5) are shown. Bar = 5 µM. Right panel: Close apposition of PfSec24a-marked tER sites and Golgi. Parasites expressing PfSec24a–mRFP and PfGRASP–GFP demonstrate a close relationship between the number and location of tER sites and Golgi, as illustrated in three representative parasites.

Lee MC, Moura PA, Miller EA, Fidock DA. Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif. Mol Microbiol. 2008 68:1535-46.