PF3D7_1022800 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), putative

Expression and localization of Kae1api interaction partners. Representative IFA images from RFA-tagged parasites are shown. IspG (top row), EF-Ts (middle row), and a putative RNA helicase (bottom row) co-localize with an apicoplast marker (ACP) and not with mitochondria. Mitochondria and nuclei were visualized with Mitotracker and DAPI-DNA stain, respectively. IFA

studies confirmed the apicoplast localization of all three proteins.

Mallari JP, Oksman A, Vaupel B, Goldberg DE. Kinase-Associated Endopeptidase 1 (Kae1) Participates in an Atypical ribosome-Aassociated complex in the apicoplast of Plasmodium falciparum. J Biol Chem. 2014 Sep 9 [Epub ahead of print]

Other associated proteins

PFID Formal Annotation
PF3D7_0305000 elongation factor Ts
PF3D7_0408900 tRNA N6-adenosine threonylcarbamoyltransferase
PF3D7_0504400 ATP-dependent helicase, putative