Blocking Unfolding Arrests Export of PNEPs. (A) Schematic of the constructs of the cell lines shown in (B). (B) Parasites expressing REX2mCherry (red) together with the mDHFR-GFP-tagged constructs (green) indicated above each panel. Two images are shown per cell line in the WR99210 (+wr)-treated samples to demonstrate that in different cells the parasite peripheral staining of the blocked protein displayed either a smooth or a more focal pattern. Merge, overlay of the red and green signals. The size bar represents 5 mm.
Grüring C, Heiber A, Kruse F, Flemming S, Franci G, Colombo SF, Fasana E, Schoeler H, Borgese N, Stunnenberg HG, Przyborski JM, Gilberger TW, Spielmann T. Uncovering common principles in protein export of malaria parasites. Cell Host Microbe. 2012 12(5):717-29.
Other associated proteins
|PF3D7_0501300||skeleton-binding protein 1|
|PF3D7_1370300||membrane associated histidine-rich protein|