Expression of PfACb in P. falciparum blood stages. Immunofluorescence assays (IFA) were used to detect PfACb (green) in P. falciparum rings (i), trophozoites (ii), schizonts (iii) and merozoites (iv) using mouse antisera against a peptide derived from PfACb. Nuclear DNA was stained with DAPI (blue). Rabbit antiserum against P. falciparum cytoplasmic protein PfNAPL (red) was used for co-localization. Yellow indicates overlap of PfACb and PfNAPL. PfACb is thus expressed in P. falciparum merozoites and is localized in the cytoplasm.
Dawn A, Singh S, More KR, Siddiqui FA, Pachikara N, Ramdani G, Langsley G, Chitnis CE. The Central Role of cAMP in Regulating Plasmodium falciparum Merozoite Invasion of Human Erythrocytes. PLoS Pathog. 2014 18;10(12):e1004520.
Other associated proteins
|PF3D7_0802600||Adenylyl cyclase, Acb|