PF3D7_0410000 erythrocyte vesicle protein 1

Upper panel: PFD0495c is exported to the erythrocyte. (iii) fluorescence image of pfd0495c-gfp expressing parasites. Fluorescence image of pfd0495c-gfp expressing parasites (iv) fluorescence and DIC image showing export of

PDF0495c chimera to the erythrocyte (e) periphery (arrow) and

intraerythrocytic spots (arrowhead).

Lower panel: PFD0495c is found within intraerythrocytic structures. 3D7 early schizonts were fixed and probed with antibodies to PFD0495c (i) and Skeleton Binding Protein (SBP1; ii) for immunofluorescence. Endogenous PFD0495c is found associated with the parasite and within intraerythrocytic structures, vesicular (arrowhead) and tubular (arrow) structures, distinct from Maurer’s Clefts (iii).

Tamez PA, Bhattacharjee S, van Ooij C, Hiller NL, Llinás M, Balu B, Adams JH, Haldar K. An erythrocyte vesicle protein exported by the malaria parasite promotes tubovesicular lipid import from the host cell surface. PLoS Pathog. 2008 Aug 8;4(8):e1000118.

Other associated proteins

PFID Formal Annotation
PF3D7_0501300 skeleton-binding protein 1