Characterization of the lysylation system in P. falciparum. Immunofluorescence assays of infected red blood cells (iRBCs) containing PfKRS-2leader-GFP-transfected P. falciparum parasites. The GFP-tagged sequence colocalizes with ACP and not with Mitotracker, indicating that it is being specifically targeted to the apicoplast, consistently with the bioinformatic predictions.

Hoen R, Novoa EM, López A, Camacho N, Cubells L, Vieira P, Santos M, Marin-Garcia P, Bautista JM, Cortés A, Ribas de Pouplana L, Royo M. Selective inhibition of an apicoplastic aminoacyl-tRNA synthetase from Plasmodium falciparum. Chembiochem. 2013 14(4):499-509.