Localization of XPD in P. falciparum 3D7 strain. A Different stages, i.e., ring, trophozoites, schizonts, and merozoites of the P. falciparum 3D7 strain, were fixed and stained with purified anti-PfXPDN antibodies. bright field image (i), image of cell stained with DAPI (ii), munofluorescently stained cell with anti-PfXPDN antibody (iii), merged images of ii and iii (iv), and merged images (v). PfXPD is mostly localized in the nuclear region during all the intraerythrocytic developmental stages (a–f). However, a partial cytoplasmic localization was also observed during trophozoite and schizont stages.
Tajedin L, Tarique M, Tuteja R. Plasmodium falciparum XPD translocates in 5'to 3' direction, is expressed throughout the blood stages, and interacts with p44. Protoplasma. 2015 Feb 24. [Epub ahead of print]