Localisation of PfCK1 in micronemes. (A) Localisation of PfCK1 and PfRON3 in schizonts and segmenters. DAPI was used to stain the nucleus and the scale bar represents 10μm. (B) Localisation of PfCK1 and AMA-1 in merozoites. DAPI was used to stain the nucleus and the scale bar represents 1μm. A punctate pattern emerges in segmenters, with one PfCK1 dot in each developing merozoite, adjacent to the rhoptry marker RON3. In line with this observation, PfCK1 colocalises with AMA-1, a protein of micronemes that is released at the very early stages of invasion.
Dorin-Semblat D, Demarta-Gatsi C, Hamelin R, Armand F, Carvalho TG, Moniatte M, Doerig C. Malaria Parasite-Infected Erythrocytes Secrete PfCK1, the Plasmodium Homologue of the Pleiotropic Protein Kinase Casein Kinase 1. PLoS One. 2015 10(12):e0139591.
Other associated proteins
|PF3D7_1136500||casein kinase 1|
|PF3D7_1252100||rhoptry neck protein 3|