MTRAP is cleaved within the micronemes. A) IFA of compound 1 (C1) treated schizonts co-labelled with mAMA1 antibodies (green) and rM-tsr (top panels), rM-mid (middle panels) or rM-tail (bottom panels) (red in respective images). Scale bars = 1 μm. C) Schematic of pre- (left half) and post- (right half) invasion merozoites, showing the predominant distribution of each protein tested as part of this study. It should be noted that all proteins show a degree of variability in labelling distributions across merozoites imaged to an extent that is not possible to depict here.
Riglar DT, Whitehead L, Cowman AF, Rogers KL, Baum J. Localization-based imaging of malarial antigens during red cell entry reaffirms role for AMA1 but not MTRAP in invasion. J Cell Sci. 2015. [Epub ahead of print]
Other associated proteins
|PF3D7_1028700||merozoite TRAP-like protein|