FPPS/GGPPS localization. Images of live parasites (FPPS/GGPPS-HA-GFP strain) expressing GFP and immunofluorescence of the FPPS/GGPPS-HA strain visualized by fluorescence or confocal microscopy. (A) Images of live parasites FPPS/GGPPS-HA-GFP by fluorescence microscopy during the intra-erythrocytic cycle of the parasite. (B) Bottom -immunofluorescence of the FPPS/GGPPS-HA strain with antibody as indicated, visualized by confocal microscopy. Top—Images of live FPPS/GGPPS-HA-GFP parasites with markers as indicated, visualized by confocal microscopy. ET1 (early rophozoites); ET2 (early trophozoites); LT (latetrophozoites); LT (late trophozoites) S1 (schizont); S2 (schizont); R (rosettes); M (Merozoites); DAPI (nucleus marker). Original magnification for all images: 1.000×

Gabriel HB, de Azevedo MF, Palmisano G, Wunderlich G, Kimura EA, Katzin AM, Alves JM. Single-target high-throughput transcription analyses reveal high levels of alternative splicing present in the FPPS/GGPPS from Plasmodium falciparum. Sci Rep. 2015. PMID: