Native PfARO exhibits nucleo-apical shuttling. Confocal immunofluorescence imaging using PfARO specific antibodies detected predominant expression of native PfARO in the nucleus during the early schizont stage parasites, which decreased with the intra-erythrocytic growth of the parasite. At later stages, native PfARO was observed to be predominantly outside the nucleus (Scale bar, 2 μm).

Mitra P, Gupta ED, Sahar T, Pandey AK, Dangi P, Reddy KS, Chauhan VS, Gaur D. Evidence for the Nucleo-Apical Shuttling of a Beta-Catenin Like Plasmodium falciparum Armadillo Repeat Containing Protein. PLoS One. 2016 11(2):e0148446.