PF3D7_0201900 erythrocyte membrane protein 3

PEXEL-independent export of PEXEL proteins does not occur in P. falciparum. (a) HRPII 4A is exported to the P. falciparum-infected erythrocyte. HRPII 4A RLE4A and HRPII 4A RLE4A Down are not exported. Scale bar, 5 mm. (b) PfEMP31–82 is exported by P. falciparum to the erythrocyte, but PfEMP3 4A RLQ4A is not. Scale bar, 5 mm.

Boddey JA, O'Neill MT, Lopaticki S, Carvalho TG, Hodder AN, Nebl T, Wawra S, van West P, Ebrahimzadeh Z, Richard D, Flemming S, Spielmann T, Przyborski J, Babon JJ, Cowman AF. Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding. Nat Commun. 2016 Feb 1;7:10470.

Other associated proteins

PFID Formal Annotation
PF3D7_0831800 histidine-rich protein II
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