Loss of apicoplast in indolmycin-treated, IPP-rescued parasites. Live cell fluorescence comparing treated and untreated ACP-DsRed/CS-eYFP P. falciparum 3D7. ACP, apicoplast acyl-carrier protein. DIC, differential interference contrast. CS, mitochondrial citrate synthase.
Pasaje CF, Cheung V, Kennedy K, Lim EE, Baell JB, Griffin MD, Ralph SA. Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum. Sci Rep. 2016 6:27531.
PubMed Article: Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum
Other associated proteins
|PF3D7_0208500||acyl carrier protein|
|PF3D7_1251700||tryptophanyl-tRNA synthetase, putative tryptophan--tRNA ligase, putative|