Fluorescent microscopy imaging of P. falciparum transfected with GFP-labelled PfATC shows distinct localization of PfATC. GFP-labelling experiments in vivo showed distinct localization of PfATC compared with the ER, supporting the hypothesis of the apicomplexian nature of the enzyme.

Lunev S, Bosch SS, Batista Fde A, Wrenger C, Groves MR. Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum. Acta Crystallogr F Struct Biol Commun. 2016 72:523-33.