(B) IFA indicates the specificity of mAb A7 in schizont stage parasites. PfRH2b (PfRH2b, red) co-stained with AMA1 (AMA1, green), DAPI for nuclei (blue) in 3D7, 3D7ΔPfRH2a and 3D7ΔPfRH2b schizont. In the merged images, areas of overlap between the red and the green signals are shown in yellow. Scale bar indicated in white represents 2 μm. (D) Nonpermeabilized W2mef merozoites show surface expression of PfRH2b using mAb A7. PfRH2b shown green (RH2b A7), DAPI for nuclei (blue) and bright field (Bf) images shown in gray. Scale bar indicates 2 μm.
Aniweh Y, Gao X, Gunalan K, Preiser PR. PfRH2b Specific Monoclonal Antibodies Inhibit Merozoite Invasion. Mol Microbiol. 2016 Jul 20.
Other associated proteins
|PF3D7_1335300||reticulocyte binding protein 2 homologue b, ALKBH5|
|PF3D7_1335400||reticulocyte binding protein 2 homologue a|