PF3D7_0917900 PfHsp70-2

Expression and localization of PfDHHC proteins in Plasmodium falciparum schizonts. Triple-HA-tagged PfDHHC proteins were localized by immuno-fluorescence using antibodies against the 3-HA tag (green). Immunofluorescence staining of each of the tagged PfDHHC proteins was compared against that of the following known localization markers (red): ERD2 (Golgi marker), BIP (endoplasmic reticulum marker), RAP1 (rhoptry marker), GAP45 (inner membrane complex marker) and MSP1 (plasma membrane marker). Nuclear staining by DAPI is shown in blue. For the staining of PfDHHC9 with GAP45 and MSP1, a late schizont, as well as an early schizont, is shown in order to differentiate between inner membrane complex and plasma membrane localization. Scale bar: 5 μm.

Tay CL, Jones ML, Hodson N, Theron M, Choudhary JS, Rayner JC. Study of Plasmodium falciparum DHHC palmitoyl transferases identifies a role for PfDHHC9 in gametocytogenesis. Cell Microbiol. 2016 18(11):1596-1610.

Other associated proteins

PFID Formal Annotation
PF3D7_0501600 rhoptry-associated protein 2
PF3D7_0528400 palmitoyltransferase
PF3D7_0930300 merozoite surface protein 1
PF3D7_1115900 palmitoyltransferase DHHC9
PF3D7_1121000 palmitoyltransferase DHHC3
PF3D7_1222700 glideosome-associated protein 45
PF3D7_1322500 palmitoyltransferase DHHC5
PF3D7_1353600 ER lumen protein retaining receptor
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