GEXP18 and PfPHIST_0801 are J-dot proteins. (A) Immunofluorescence using the J-dot marker PfHsp70x shows good colocalization with the GEXP18GFP chimera. (B) Immunofluorescence using the J-dot marker PfHsp70x shows good colocalization with PfPHIST_0801GFP. 70x, PfHsp70x; DIC, differential interference contrast, PHISTC, PfPHIST_0801. PfHsp70x and PfGEXP18 are found in a common protein complex. As PfGEXP18 is only found at the J-dots (A), this entire complex is likely to be localized to the J-dots. There is a good colocalization between PfPHIST_0801 and PfHsp70x (B) suggesting that PfPHIST_0801, as well as PfGEXP18, localizes to the J-dots.
Zhang Q, Ma C, Oberli A, Zinz A, Engels S, Przyborski JM. Proteomic analysis of exported chaperone/co-chaperone complexes of P. falciparum reveals an array of complex protein-protein interactions. Sci Rep. 2017 7:42188.
Other associated proteins
|PF3D7_0402400||Plasmodium exported protein, unknown function gametocyte exported protein 18|
|PF3D7_0801000||Plasmodium exported protein PHISTc|