PF3D7_0302500 cytoadherence linked asexual protein 3.1

Localization of RhopH1/clag3 and RhopH3 in infected erythrocytes when RhopH2 expression is knocked down. Representative immunofluorescence analysis of erythrocytes infected with RhopH2-HAglmS parasites grown in 0 mM or 2.5 mM GlcN. Cells fixed with acetone/methanol and labelled with anti-HA antibody to detect RhopH2 IFAs and other antibodies, as indicated. the localization of RhopH3 and to a lesser extent RhopH1/clag3 was affected when RhopH2 expression was knocked down.

Counihan N, Chisholm SA, Bullen HE, Srivastava A, Sanders PR, Jonsdottir TK, Weiss GE, Ghosh S, Crabb BS, Creek DJ, Gilson PR, de Koning-Ward TF. Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate. Elife. 2017 Mar 2;6. pii: e23217

Other associated proteins

PFID Formal Annotation
PF3D7_0905400 high molecular weight rhoptry protein 3
PF3D7_0929400 high molecular weight rhoptry protein 2