Validation of RH5 mAbs by Immunofluroscence Microscopy. Smears of 3D7 late stage schizont were co- stained with RH5(5) (c) (7) (d) and (12) (e) (first column, green) and antibodies against other invasion markers RH1, EBA175 and AMA1 respectively (second column, red). Parasite nuclei were stained with DAPI (blue). In the merged images, areas of overlap between the red and the green signals are shown in yellow. Bright field indicates the outline of the schizont. Scale bar =2μm.
Aniweh Y, Gao X, Hao P, Meng W, Lai SK, Gunalan K, Chu TT, Sinha A, Lescar J,
Chandramohanadas R, Li HY, Sze SK, Preiser PR. RH5-Basigin interaction induces
changes in the cytoskeleton of the host RBC. Cell Microbiol. 2017 Apr 13 [Epub ahead of print] PMID: 28409866
Other associated proteins
|PF3D7_0402300||reticulocyte binding protein homologue 1 normocyte binding protein 1|
|PF3D7_0424100||reticulocyte binding protein homologue 5|
|PF3D7_0731500||erythrocyte binding antigen-175|