PF3D7_1220900 heterochromatin protein 1

Co-localization of ectopic PF3D7_1209300-GFP and PfHP1 in trophozoites. The white frame refers to the magnified view in the rightmost image. DIC, differential interference contrast. Scale bar, 5 μm. Results are representative of three biological replicate experiments. IFAs demonstrated that an ectopically expressed green fluorescent protein (GFP)-tagged version of this factor localized to distinct spots at the nuclear periphery, in close proximity to the chromosome end marker PfHP1 (HP1, heterochromatin protein 1.

Bertschi NL, Toenhake CG, Zou A, Niederwieser I, Henderson R, Moes S, Jenoe P, Parkinson J, Bartfai R, Voss TS. Malaria parasites possess a telomere repeat-binding protein that shares ancestry with transcription factor IIIA. Nat Microbiol. 2017 2:17033.

Other associated proteins

PFID Formal Annotation
PF3D7_1209300 telomere repeat-binding zinc finger protein, putative