PF3D7_0930300 merozoite surface protein 1

To establish the effects of SERA5 loss on parasite growth, we compared the replication rates of mock-treated and RAP-treated floxSERA5-1B6 and floxSERA5-3B6 clones, using the parental 1G5DC clone as a controlIFA of mature schizonts of control (DMSO-treated) and RAP-treated integrant clone floxSERA5-1B6 ~44 h following treatment. No SERA5-specific signal was detectable in the majority (~98%) of the rapamycin-treated population. Scale bar, 5 μm

Collins CR, Hackett F, Atid J, Tan MSY, Blackman MJ. The Plasmodium falciparum pseudoprotease SERA5 regulates the kinetics and efficiency of malaria parasite egress from host erythrocytes. PLoS Pathog. 2017 13(7):e1006453.

Other associated proteins

PFID Formal Annotation
PF3D7_0207600 serine repeat antigen 5